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The expression of NOX redirected secondary metabolism. The NOX-expression strains produced more erythromycin in the minimal liquid medium (A) and the complex medium (B), while the pigment production in the NOX-expression strains reduced dependent on the level of NOX expression in the minimal liquid medium (C). Data are shown as mean ± standard deviation from at least three independent experiments for erythromycin determination. *, P-value < 0.05.
