| Statin: HMG-CoA reductase inhibitor | |
| Usage/dosage | Lovastatin: 20–80 mg/day, taken with dinner |
| Pravastatin: 10–40 mg/day, evening administration is more effective | |
| Simvastatin: 20–40 mg/day, evening administration is more effective | |
| Fluvastatin: 20–80 mg/day, evening administration is more effective | |
| Atorvastatin: 10–80 mg/day, time of administration is not significantly relevant | |
| Rosuvastatin: 5–20 mg/day, time of administration is not significantly relevant | |
| Pitavastatin: 1–4 mg/day, time of administration is not significantly relevant | |
| Follow-up test | Lipid profile, liver function test, muscle enzymes (when there is unexplainable muscle pain or muscle weakening) |
| Adverse reaction | Indigestion, heartburn, abdominal pain, hepatotoxicity, muscle toxicity, diabetes |
| Contraindication | Active or chronic liver disease, pregnancy, and breastfeeding are absolute contraindications. Combining with cyclosporin, macrolide antibiotics, antifungal agents, or cytochrome P-450 inhibitors is a relative contraindication and requires caution. |