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. 2019 Aug 7;8(2):78–131. doi: 10.12997/jla.2019.8.2.78
Fibrate
Usage/dosage Bezafibrate: 400–600 mg/day, 1–3 times a day, after meals
Fenofibrate: 160–200 mg/day, once a day, immediately after meals
Gemfibrozil: 600–1,200 mg/day, twice a day, 30 minutes before meals (avoid combination therapy with statin)
Follow-up test Lipid profile, liver function test, general blood test, CK (when there is unexplainable muscle pain or muscle weakness)
Adverse reaction Indigestion, cholesterol gallstones, myopathy
Contraindications Severe liver disease, gallbladder disease, and hypersensitivity to fibrate is absolute contraindications, and use of the drug requires precaution for individuals with reduced kidney function