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. 2018 Oct 25;60(5):585–598. doi: 10.1111/jcpp.12999

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© 2018 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Characterization of the four co‐expression modules associated with the intermediate phenotypes of Williams syndrome (WS). (A‐D) Bar plots of module eigengene (ME) expression for (A) M4 module, (B) M11 module, (C) M12 module, and (D) M22 module. (E) The top three enriched Gene Ontology (GO) biological processes for each module. The red line indicates the Z‐score threshold (Z = 2). (F) The top three enriched KEGG pathways. The red line indicates a false discovery rate (FDR) threshold of 0.05. (G and H) The top 15 hub genes of (G) M11 module and (H) M4 module