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Predicted BMDL10‐BMDU10 values for acute liver toxicity of AFB1 in human obtained by the PBK modeling‐facilitated reverse dosimetry approach using data from fresh human hepatocytes.[ 54 ] The predicted BMDL10‐BMDU10 (white rectangle bars) are compared to the estimated doses that can cause a risk of acute aflatoxicosis and possibly fatality in humans[ 4 , 9 ] (gray rectangle bars).
