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. 2020 Jul 17;8:559. doi: 10.3389/fcell.2020.00559

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Copyright © 2020 Wang, Zheng, Pan, Yao, Gao, Wang and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of icariin on metabolic parameters in kidney damage rats. (A) The 24 h urinary volume, (B) 24 h proteinuria, (C) Blood urea nitrogen (BUN), (D) Serum creatinine (Src), (E) Urinary creatinine, (F) Creatinine clearance, and (G) 24 h urinary albumin excretion were measured by ELISA. (H) The ratio of kidney weight to body weight. (I) Triglyceride, (J) Total Cholesterol, (K) Non-esterified fatty acid, (L) LDL-Cholesterol and (M) HDL-Cholesterol were measured by ELISA. Data are expressed as mean ± SD (n = 10). *p < 0.05, **p < 0.01, compared with the normal control group; ^#p < 0.05, ^##p < 0.01, compared with the Model group.