Table 3.
Metric variables with a statistically significant difference between cases and controls within at least one participant cohort.
| PSS | EUCLID | ||||||
|---|---|---|---|---|---|---|---|
| Variable | Statistical test | Number of days or blood test value (cases) | Number of days or blood test value (controls) | P-value | Number of days or blood test value (cases) | Number of days or blood test value (controls) | P value |
| Days from admission to sample tested (all participants) | T-test (mean) | 15 | 10 | <0.001 | 10 | 9 | 0.384 |
| Mann–Whitney (median) | 10 | 8 | 0.001 | 6 | 3 | 0.028 | |
| Days from admission to sample tested (Participants admitted from their own home) | T-test (mean) | 15 | 11 | <0.001 | 8 | 7 | 0.575 |
| Mann–Whitney (median) | 10 | 8 | 0.028 | 5 | 2 | 0.016 | |
| Days from admission to sample tested (Participants admitted from another Hospital) | T-test (mean) | 19 | 10 | <0.001 | 22 | 13 | 0.225 |
| Mann–Whitney (median) | 12 | 7 | 0.001 | 6 | 9 | 0.221 | |
| Days from admission to sample tested (Participants admitted from the Emergency department) | T-test (mean) | 12 | 8 | 0.039 | 8 | 13 | 0.337 |
| Mann–Whitney (median) | 8 | 5 | 0.368 | 9 | 10 | 0.562 | |
| Days before the Index sample when a CDI test occurred (this could occur before the admission of interest) | T-test (mean) | 28.9 | 11.9 | 0.0003 | 57 | 30 | 0.002 |
| Mann–Whitney (median) | 12.5 | 176 | 0.232 | 37 | 16 | 0.005 | |
| Duration of antibiotics | T-test (mean) | 6.3 | 8.7 | <0.001 | 12 | 13 | 0.900 |
| Mann–Whitney (median) | 6 | 4 | <0.001 | 7 | 7 | 0.541 | |
| Duration of PPIs | T-test (mean) | 17 | 12 | 0.0003 | 104 | 131 | 0.786 |
| Mann–Whitney (median) | 11 | 8 | 0.0001 | 17 | 11 | 0.688 | |
| Duration of GI drugs | T-test (mean) | 8 | 5 | <0.001 | 24 | 91 | 0.379 |
| Mann–Whitney (median) | 3 | 3 | 0.0001 | 4 | 5 | 0.779 | |
| Duration of steroids | T-test (mean) | 16 | 8 | <0.001 | 12 | 60 | 0.546 |
| Mann–Whitney (median) | 7 | 4 | <0.001 | 12 | 8 | 0.717 | |
| Days from surgery to Index sample | T-test (mean) | 17 | 12 | 0.002 | 26 | 19 | 0.090 |
| Mann–Whitney (median) | 10 | 8 | 0.125 | 22 | 15 | 0.131 | |
| Serum creatinine (mg/dL) | T-test (mean) | 2.3 | 1.7 | 0.0001 | 1.5 | 1.2 | 0.023 |
| Mann–Whitney (median) | 1.3 | 1 | <0.001 | 1.0 | 0.8 | 0.023 | |
| White cell count (mm3) | T-test (mean) | 13.2 | 12.6 | 0.759 | 13.0 | 9.7 | <0.001 |
| Mann–Whitney (median) | 11.4 | 9.4 | <0.001 | 11.6 | 8.5 | <0.001 | |
| Serum albumin (g/L) | T-test (mean) | 27.7 | 29.4 | 0.013 | 26 | 28.6 | 0.227 |
| Mann–Whitney (median) | 27 | 29 | 0.014 | 27 | 31 | 0.110 | |