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. 2018 Nov 26;285(4):367–380. doi: 10.1111/joim.12855

Figure 5.

Figure 5

Possible therapeutic targeting of oxysterols in colitis. Small‐molecule agonists and antagonists could be used to inhibit the activity of the oxysterol receptors LXR and GPR183, respectively. Alternatively, drugs affecting the synthesis or degradation of oxysterols could be employed to modulate oxysterol function.