Table 1.
Clinical information of HB patients.
| Sample ID | HB-303 | HB-243 | HB-279 | HB-282 | HB-284 | HB-295 |
|---|---|---|---|---|---|---|
| Age (months) | 69 | 52 | 79 | 12 | 83 | 26 |
| Type of sample | Primary | Intrahepatic relapse | Primary | Primary | Peritoneal metastasis at relapse | Primary |
| R, resection; LT, liver transplant |
R | LT | LT | R | R | R |
| Sex | F | M | M | M | M | F |
| Vascular invasion Y/N | N | Y | Y | N | n/a | Y |
| S, solitary; M, multiple nodules | M | M | M | S | n/a | M |
| Metastasis Y/N | N | N | N | N | n/a | Y |
| Main histological component | Fetal | Embryonal | Embryonal + Macrotrabecular | Embryonal | Embryonal | Fetal |
| PRETEXT | II | n/a | IV | II | n/a | II |
| Chemotherapy protocol | Cisplatin 4 cycles | Carboplatin + Etoposide | SIOPEL-4 | SIOPEL-3 + SIOPEL-6 | Etoposide + Cisplatin | SIOPEL-4 |
| AFP serum at diagnosis (ng/mL) | 158,645 | 6,000 | 1,000,000 | 1,286,000 | 2,162 | 585,350 |
| AFP serum post-chemoth. (ng/mL) | 26,000 | 5,000 | 30,000 | 1,000,000 | 1,089 | 1,400 |
PRETEXT, Pre-treatment extent of disease, radiological staging system for primary pediatric liver malignancies. AFP, alpha-fetoprotein. n/a, information is not available. Information adapted from (50).