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. Author manuscript; available in PMC: 2021 Jun 16.
Published in final edited form as: Biochemistry. 2020 Jun 4;59(23):2171–2181. doi: 10.1021/acs.biochem.0c00176

Figure 1.

Figure 1.

Interactions between IL-31 and its receptors. The cartoon model of IL-31 structure was generated using the feline sequence. (a.) The ternary complex formed between IL-31, IL-31RA, and OSMR. Different domains of both receptors are indicated in the figure legend. (b.) Binding sites for the interaction between human IL-31 (hIL-31) and its receptors as described by Le Saux et at13. Residues corresponding to the hIL-31 sequence are indicated in parenthesis.