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Specific binding sites revealed for fIL31RA-1FNIII and fOSMR-ECD. The shared site (orange) is composed of B-helix, BC loop, C-helix, and CD loop. The binding site for fIL31RA-1FNIII (green), site II, includes A helix and C helix. The binding site for fOSMR-ECD (purple), site III, comprises the N-terminal of AB loop and D-helix.
