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Summary of experimental determined dissociation constants (KD) using yeast surface display and surface plasmon resonance. Error bars represent the standard error of the mean of at least 3 independent measurements. ND, not determined.
| Average KD values [nM] | |||||
|---|---|---|---|---|---|
| Name | Yeast Surface Display | Hill Coefficient | Surface Plasmon Resonance | Fit | Chi2 (RU2) |
| fOSMR-ECD | 10.3 ± 0.5 | 0.99 ± 0.04 | 3.8 | 1:1 | 0.84 |
| fIL31RA-1FNIII | 106 ± 2.7 | 1.00 ± 0.01 | ND | 1:1 | ND |
| mAb #1 | 0.26 ± 0.01 | 0.99 ± 0.04 | 0.3 | 1:1 | 3.17 |
