Figure 1.

Unrooted maximum likelihood tree demonstrating the phylogenetic structure of core genomes of Streptococcus suis serotype 2 CC1 isolates from the Netherlands and international CC1 reference genomes. Country of isolation is indicated as well as the sequence type of each isolate. Black stars indicate s. suis isolates from human patients. Complete reference genomes are indicated in blue, and isolates 2071319 and 2150651, both responsible for infecting the same patient, are indicated in red. The tree was generated using SNPs in the core genome using RAxML until it converged at the bootstopping criterion, which was at 650 bootstraps [Colour figure can be viewed at wileyonlinelibrary.com]