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. 2018 Sep 27;17(1):27–38. doi: 10.1111/idh.12364

Table 4.

Summary of findings table on body of the estimated evidence profile (GRADE, 2015) and appraisal of the strength of the recommendation regarding the effectiveness of dentifrice on plaque regrowth, in 4‐day nonbrushing plaque regrowth models

Determinants of quality Plaque scores
Study design (Appendix S1) RCTs crossover designs
# studies n = 8 25
# comparison n = 25 (Figure 1)
Risk of bias (Appendix S2) Low
Consistency (Table 3) Rather consistent
Directness (Dentifrice slurry) Indirect
Precision (Table 3) Rather precise
Publication bias (Appendices S4b/S5b/S6b) Possible
Magnitude of the effect Small
Strength of the recommendation based on the body of evidence Moderate
Direction of recommendation Weak in favour of the use of dentifrice