Table 1.

Haematology and blood biochemistry findings in study I

	Ciclesonide 450 μg	Ciclesonide 900 μg	Ciclesonide 1800 μg	Dexamethasone
PCV [%]
Day 0	36 ± 4	37 ± 5	36 ± 7	36 ± 7
Day 14	35 ± 4	34 ± 6	34 ± 6	37 ± 5
Day 21	37 ± 5	36 ± 5	35 ± 6	35 ± 5
Total proteins [g/L]
Day 0	75.1 ± 7.3	75.6 ± 6.9	72.6 ± 9.0	74.9 ± 7.4
Day 14	73.9 ± 6.1	74.4 ± 4.7	71.9 ± 6.4	72.4 ± 2.3
Day 21	75.2 ± 7.1b	75.1 ± 6.6b	72.0 ± 08.9	65.7 ± 2.8a
WBC [×109/L]
Day 0	7.1 ± 1.6	7.5 ± 1.1	7.1 ± 1.6	7.3 ± 1.5
Day 14	7.3 ± 2.0	6.9 ± 1.4	7.8 ± 1.6	8.3 ± 1.7
Day 21	8.1 ± 1.8	7.3 ± 2.8	7.4 ± 1.0	6.5 ± 1.6
Segmented neutrophils [×109/L]
Day 0	4.7 ± 1.3	5.2 ± 1.1	4.6 ± 1.3	4.8 ± 1.3
Day 14	5.0 ± 1.7	4.4 ± 1.1	5.4 ± 1.7	6.2 ± 1.3
Day 21	5.5 ± 1.5	4.9 ± 2.5	9.4 ± 1.1	4.3 ± 1.2
Lymphocytes [×109/L]
Day 0	2.0 ± 0.4	1.8 ± 0.3	1.9 ± 0.5	2.1 ± 0.7
Day 14	2.0 ± 0.4	2.0 ± 0.5	2.0 ± 0.6	1.7 ± 0.5a
Day 21	2.2 ± 0.5b	1.9 ± 0.3	2.1 ± 0.6	1.8 ± 0.4

Data presented as mean ± s.d. PCV, packed cell volume; WBC, white blood cells.

^aDifferent from the same treatment at day 0 (P≤0.002).

^bDifferent from dexamethasone at the same time point (P≤0.007).