Table 2.
Haematology and blood biochemistry findings in study II
| Ciclesonide 1687.5 μg | Ciclesonide 2700 μg (A) | Ciclesonide 2700 μg (B) | Dexamethasone | |
|---|---|---|---|---|
| PCV [%] | ||||
| Day 0 | 34 ± 4 | 35 ± 5 | 34 ± 3 | 36 ± 4 |
| Day 14 | 32 ± 5 | 32 ± 4 | 32 ± 4 | 31 ± 4a |
| Day 21 | 34 ± 4 | 33 ± 5 | 34 ± 4 | 35 ± 4 |
| Total proteins [g/L] | ||||
| Day 0 | 71.8 ± 6.4 | 71.6 ± 8.0 | 70.6 ± 3.7 | 75.1 ± 6.3 |
| Day 14 | 70.8 ± 5.1 | 70.1 ± 4.1 | 69.3 ± 4.9 | 69.8 ± 3.6a |
| Day 21 | 73.0 ± 4.5b | 71.5 ± 5.8b | 70.4 ± 6.3 | 65.5 ± 3.8a |
| WBC [×109/L] | ||||
| Day 0 | 6.8 ± 2.2 | 7.4 ± 2.0 | 6.49 ± 1.4 | 7.4 ± 1.9 |
| Day 14 | 7.6 ± 2.8 | 7.5 ± 1.7 | 7.0 ± 2.0 | 8.3 ± 1.8 |
| Day 21 | 7.1 ± 2.2 | 6.8 ± 2.2 | 7.2 ± 2.0 | 7.0 ± 1.1 |
| Segmented neutrophils [×109/L] | ||||
| Day 0 | 4.5 ± 1.6 | 4.9 ± 1.4 | 4.2 ± 1.2 | 4.8 ± 1.5 |
| Day 14 | 5.2 ± 2.5 | 4.8 ± 1.1 | 4.7 ± 2.0 | 6.2 ± 1.4 |
| Day 21 | 4.5 ± 1.8 | 4.4 ± 1.7 | 4.8 ± 1.5 | 4.8 ± 1.0 |
| Lymphocytes [×109/L] | ||||
| Day 0 | 1.9 ± 0.5 | 2.0 ± 0.6 | 1.8 ± 0.4 | 2.1 ± 0.6 |
| Day 14 | 1.9 ± 0.3 | 2.1 ± 0.4 | 1.7 ± 0.4 | 1.7 ± 0.6 |
| Day 21 | 2.0 ± 0.4 | 2.0 ± 0.4 | 2.0 ± 0.6 | 1.7 ± 0.3 |
Data presented as mean ± s.d. PCV, packed cell volume; WBC, white blood cells.
a
Different from the same treatment at day 0 (P≤0.002).
b
Different from dexamethasone at the same time point (P≤0.002).