Table 1.
Histopathological and molecular profile of ependymomas without evidence of RELA‐C11orf or YAP1 fusion.
| Cases | Age (y) | IHC NF‐κB p65 | FISH RELA BA | FISH C11orf95 BA | DNA methylation assay | Chromotripsis chr11 | RT‐PCR (transcript type 1 and 2) | RNAsequencing |
|---|---|---|---|---|---|---|---|---|
| 23 | 1 | − | − | + | EPN, RELA | − | − | ND |
| 24 | 1 | − | Failed | Failed | Undetermined | + | − | MAML2‐ASCL2 t(11;11)(q21;p15.5) |
| 25 | 8 | − | Failed | Failed | Undetermined | − | − | ND |
| 34 | 10 | − | − | − | Undetermined | − | − | MARK2‐ADCY3 t(11;2)(q13.1;p23.3) |
| 35 | 11 | − | − | − | Undetermined | − | ND | ND |
| 36 | 2 | − | Failed | Failed | Failed | NA | ND | ND |
Abbreviations: NA = not available; ND = not done.