Figure 4.

Effect of COS on the Hair Growth in C57BL/6 Mice. COS‐treated mouse epidermal cells were impaired in hair follicle neogenesis when combined with human DP spheres. A, A schematic illustration of the experimental procedure is shown. B, Hair follicles were ordinarily induced when control and COS‐treated mouse epidermal cells (10⁶ cells) were implanted together with human DP spheres (10⁶ cells; 100 DP spheres). C, Total induced hair follicles were counted at each injection site, and data are shown as means ± SD of quadruplicate per experiment from three independent experiments (*P < .05, **P < .01)