Table 3.

Dosing of currently available antiobesity drugs.

Drug	Trade Name (s)	Recommended Dose	DEA schedule	Comments
Phentermine	Adipex-P	18.75–37.5 mgQD^a	IV	Recommended TID dosing is 30–60 min before meals. QD dosing is in the morning. Avoid dosing close to bedtime.
	Fasti n	30 mg QD
	Suprenza	15–30 mg QD
	Lomaira	8 mgTID
Diethylpropion	Tenuate	25 mgTID	IV	As above
	Tenuate Dospan	75 mg QD	IV	As above
Phendimetrazine	Bontril	35 mgTID	III	As above
	Prelu-2	105 mg QD	III	As above
Benzphetamine	Didrex	25–50 mgTID	III	Recommended TID dosing is 30–60 min before meals.
Orlistat	Xenical	120 mgTID	None	Recommended to take at mealtime. Dosing is same for adults and adolescents.
	Alii	60 mgTID	None
Phentermine/Topiramate	Qsymia	7.5/46 mg QD 15/92 mg QD	IV	Start at 3.75/23 mg QD. Increase to 7.5/46 mg after 2 weeks. If weight loss is <3% after 3 months, discontinue or increase dose to 15/92 mg QD. Consider using a transition dosing of 11.25/69 mg while moving to 15/92 mg. Discontinue if weight loss is <5% after 3 months on the 15/92 mg dose.
Lorcaserin	Belviq	10 mg BID	IV	Discontinue if weight loss is <5% after 3 months.
	Belviq XR	20 mg QD	IV	Discontinue if weight loss is <5% after 3 months.
Naltrexone/Bupropion	Contrave	16/180 mg BID	None	Available as 8/90 mg tablets only. Start 1 tablet every morning. Increase to 1 tablet BID during second week. Increase to 2 in the morning and 1 in the evening during third week. From Week 4, dose 2 tablets BID.
Liraglutide 3.0 mg	Saxenda	3 mg QD	None	Available as a pre-filled, multi-dose injector pen that delivers solution in selected doses. Start 0.6 mg QD. At weekly intervals, increase the dose by 0.6 mg until 3.0 mg QD dose is reached. Inject subcutaneously in the abdomen, thigh or upper arm. Discontinue if weight loss is <4% after 4 months.

QD, once daily; BID, two times daily; TID, three times daily.