TABLE 3.

Canonical pathways impacted by the TPT at 24 h differentially expressed genes.

Ingenuity canonical pathways	Ratio	z-score	−log(p-value)
p53 signaling	0.28	2.71	7.89
Molecular mechanisms of cancer	0.18	NaN	7.15
Estrogen-mediated S-phase Entry	0.46	−2.31	5.98
Cell cycle: G2/M DNA damage checkpoint regulation	0.34	1	5.91
Role of BRCA1 in DNA damage response	0.28	−0.54	5.67
Mitotic roles of polo-like kinase	0.29	0.26	5.3
Cell cycle control of chromosomal replication	0.30	NaN	5.15
Breast cancer regulation by stathmin1	0.19	NaN	4.68
NER pathway	0.22	−0.23	4.28
Axonal guidance signaling	0.15	NaN	4.24
Cell cycle: G1/S checkpoint regulation	0.25	1.07	4.04

NaN, No activity pattern detected.