Table 3.

Parameters/methods/settings leading to best repeatability for different activity uptake groups

	Heterogeneous inserts	High uptake spheres	Low uptake spheres
Reconstruction	Minor impact	Minor impact	PSF+TOF
Matrix/voxel size	Minor impact	Minor impact	Smaller voxel size (2 × 2 × 2 mm)
Scan duration	300 s	300 s	300 s
Smoothing (FWHM)	6/8 mm	6/8 mm	0 mm
Discretization method	FBW (bin width 0.25)	FBW (bin width 0.25)	FBW (bin width 0.05)
Segmentation method	Minor impact	Minor impact	CT‐based segmentation