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. 2018 Nov 15;30(1):7–16. doi: 10.1111/pai.12990

Table 1.

Unmet needs in pediatric patients with asthma

Lack of clinical efficacy and safety evidence of biologics in patients <6 years
Limited availability of non‐steroid‐based alternative therapies
Lack of available therapies for children with severe asthma
Difficult diagnosis in children
Scarcity of studies on allergen immunotherapy in children
Limited access to specialist pediatric asthma care in some countries
No uniform definition of pediatric asthma or pediatric asthma control
Inadequate pediatric focus in current clinical practice guidelines
Lack of data on asthma endotypes/phenotypes
Lack of well‐defined pediatric treatable traits
Lack of molecular studies
Lack of data on personalized treatment strategies based on a phenotype (endotype) approach
Lack of treatment options for comorbidities