Table 2.

Biotechnological inhibitors used in the present study.

Inhibitor	Nature	Target	References
Lanadelumab (DX-2930)	Human monoclonal antibody	Plasma kallikrein	(26)
DX-4012	Human monoclonal antibody	Factor XIIa	(27)
DX-2300	Human monoclonal antibody	Tissue kallikrein (KLK-1)	(28)
DX-1000	Kunitz-type inhibitor	Plasmin	(29)