Table 2. Allelic profiles of antibiotic resistant genesa and antibiotic susceptibility of the Vietnamese isolatesb.
| Locus | Antibiotic susceptibility | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gyrA | penA | rpoB | NEIS0123 | NEIS0414 | NEIS1320 | NEIS1525 | NEIS1600 | NEIS1609 | NEIS1635 | NEIS1753 | AM | CIP | CTX | CRO | RI | MRP | CL | |
| NMB_VN2013 | 2 | 587 | 42 | 1446 | 1 | 32 | 1338 | 1315 | NA* | 7 | NA* | I | S | S | S | S | S | R |
| 0.42 | 0.004 | 0.016 | 0.002 | 0.25 | 0.064 | 62 | ||||||||||||
| NMB_VN2014 | 2 | 587 | 42 | 1446 | 1 | 32 | 1338 | NA | NA* | 1086 | NA* | I | S | S | S | I | S | R |
| 0.5 | 0.008 | 0.016 | 0.004 | 1.5 | 0.094 | 256 | ||||||||||||
| NMB_VN2015 | 2 | 587 | 42 | 1446 | 1 | 32 | 1338 | 1315 | NA* | 7 | 2242 | I | S | S | S | S | S | R |
| 0.62 | 0.008 | 0.023 | 0.002 | 0.125 | 0.064 | 64 | ||||||||||||
Notes.
An allele number was assigned to each locus based on its DNA sequence using PubMLST database (https://pubmlst.org/) (Jolley & Maiden, 2010).
Antibiotic susceptibility of isolates was examined using E-test strip (bioMerieux, France) and interpreted according to CLSI 2018 breakpoints (CLSI, 2018).
- NA*
- new, unassigned alleles identical at said locus
- I
- Intermediate
- S
- Susceptible
- R
- Resistance
Numbers below each susceptibility interpretation indicate MIC (µg/ml) values.