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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: ACS Chem Neurosci. 2020 Jun 18;11(13):2019–2030. doi: 10.1021/acschemneuro.0c00324

Figure 1.

Figure 1.

Electrophysiology measurement (patch clamp). A) Current response with HMC3 human microglia cells. Data (n = 12) were normalized in response to maximum current measured with 1 mM GABA and depicted as mean and SEM. EC50 was calculated by non-linear regression; B) 10 second average current sweeps of increasing concentrations of GABA with HMC3 cells; C) Current response with immortalized human and mouse microglia cells.24 Data (n = 16) were normalized in response to maximum current measured with 1 mM GABA and depicted as mean and SEM. D) 10 second average current sweeps of increasing concentrations of GABA with immortalized human microglia cells. EC50 values were calculated by non-linear regression.