Patient’s second kidney biopsy findings. Immunofluorescence showed (A) granular immunoglobulin G (IgG), (B) granular C3, (C) granular C1q, and (D) granular IgG3 deposition in the mesangial area and along the capillary wall on frozen tissue; (E) trace κ light chain deposition on frozen tissue; and (F) strong granular λ light chain deposition in the mesangial area and along the capillary wall on frozen tissue (A-F: original magnification, ×200). (G) Light microscopy shows membranoproliferative glomerulonephritis change in glomeruli (periodic methenamine silver and Masson trichrome stain; original magnification, ×400). (H) Electron-dense deposits in the mesangial, subendothelial, and segmental subepithelial areas on electron microscopy (original magnification, ×5,000).