Table 3.
Characteristics of Patients With Improved Kidney Function After Foam Sclerotherapy
| Age, y | Sex | Mutation Class | Baseline Scr, mg/dL | Baseline CLcr, mL/min | Change in CLcr, mL/mina | Time Interval, yb | Baseline Total Kidney Volume. mL | Total Kidney Volume Reduction, %c | Time Interval, yd | Change in MCIC Post-FS |
|---|---|---|---|---|---|---|---|---|---|---|
| 30s | F | PKD1 protein-truncating | 0.7 | 83 | +13 | 1.56 | 1,071 | −30 | 1.32 | 1D →1C |
| 40s | F | PKD2 | 0.7 | 107 | +24 | 1.91 | 1,798 | −5 | 0.68 | 1C →1C |
| 40s | F | No mutation detected | 0.8 | 193 | +31 | 1.33 | 972 | −51 | 0.97 | 1C → 1B |
| 30s | M | PKD1 protein-truncating | 1.0 | 103 | +11 | 1.84 | 1,807 | +26 | 1.62 | 1D → 1D |
Note: Conversion factor for units: Scr in mg/dL to μmol/L, ×88.4.
Abbreviations: CLcr, measured creatinine clearance; FS, foam sclerotherapy; MCIC, Mayo Clinic imaging class; Scr, serum creatinine.
Change in CLcr after sclerotherapy from most recent follow-up.
Time interval for the change in CLcr.
Change in total kidney volume after sclerotherapy from most recent magnetic resonance imaging.
Time interval for the change in total kidney volume.