Table 3.
Odds ratios for the variables as investigated by univariate and multivariable analyses as possible factors of minimal hepatic encephalopathy in patients having liver cirrhosis
| Variables | Univariate, OR (95% CI) | P-value | Multivariable, OR (95% CI) |
P-value |
|---|---|---|---|---|
| Age (years) | 0.960 (0.89-1.31) | 0.259 | ||
| Sex (male vs. female) |
2.37 (0.184-5.595) | 0.509 | ||
| Education (years) |
0.75 (0.513-1.098) | 0.139 | ||
| Etiology (alcohol vs. non-alcohol) |
2.32 (0.29-6.54) | 0.427 | ||
| Hemoglobin (g/dl) |
0.994 (0.87-1.13) | 0.933 | ||
| Total leucocyte count (/mm3) |
1.0 (0.99-1.0) | 0.233 | ||
| Platelet (/mm3) | 1.016 (1.0-1.03) | 0.057 | ||
| Urea (mg/dl) | 1.06 (0.99-1.13) | 0.96 | ||
| Creatinine (mg/dl) |
0.41 (0.01-9.83) | 0.58 | ||
| Sodium (mEq/l) | 0.97 (0.83-1.14) | 0.75 | ||
| Potassium (mEq/l) | 1.07 (0.90-1.28) | 0.39 | ||
| Bilirubin (g/dl) | 1.00 (0.61-1.66) | 0.97 | ||
| AST (IU/l) | 1.01 (0.99-1.03) | 0.74 | ||
| ALT (IU/l) | 0.96 (0.94-0.99) | 0.015 | ||
| Albumin (g/dl) | 2.93 (2.39-3.24) | 0.007 | ||
| ALP (IU/l) | 1.00 (0.994-1.01) | 0.614 | ||
| Prothrombin time (s) |
0.74 (0.51-1.06) | 0.107 | ||
| CTP score | 1.79 (1.25-2.13) | 0.029 | 1.83 (1.25-2.19) |
0.031 |
| MELD score | 1.57 (1.04-2.67) | 0.031 |
OR – odds ratio, CI – confidence interval, CTP – Child-Turcotte-Pugh, MELD – model of end stage liver disease, MHE – minimal hepatic encephalopathy, NMHE – non-minimal hepatic encephalopathy, AST – aspartate transaminase, ALT – alanine transaminase, INR – international normalized ratio