Table 2.

Estimates and effect sizes for the full longitudinal model of the association of IIV and entorhinal cortical thickness

	Estimate	S.E.	df	F	t	p	r
Intercept	4.760	0.150	731.91	1001.20	31.64	<0.001	0.760
Age	−0.016	0.002	730.67	60.10	−7.75	<0.001	0.276
Gender	−0.029	0.027	731.14	1.13	−1.06	0.288	0.039
APOE ε4 status	0.009	0.031	730.63	0.09	.31	0.760	0.011
Aβ status	−0.065	0.031	731.50	4.40	−2.10	0.036	0.077
Mean NP Score*	0.163	0.022	730.99	53.31	7.30	<0.001	0.261
Visit	−0.0005	0.0008	701.81	0.38	−0.61	0.539	0.023
Baseline IIV	−0.051	0.038	749.07	1.76	−1.33	0.185	0.049
IIV × Visit	−0.005	0.0008	720.04	36.72	−6.06	<0.001	0.220

APOE ε4 status = presence or absence of at least one ε4 allele; Aβ = Amyloid-β; IIV = intraindividual cognitive variability; S.E. = standard error of the estimate; df = degrees of freedom.

^*Mean NP score is the mean of the six baseline neuropsychological age-, sex-, and education-adjusted z-scores. The six scores were Animal Fluency and Boston Naming Test (language); Trail Making Test Parts A and B (processing speed/executive); and Auditory Verbal Learning Test Delayed Recall and Recognition (memory).

Significant effects (p < 0.05) appear in bold font.

Effect size (r values) interpretation: small=0.10, medium=0.30, large=0.50 (Cohen, 1992).