Table 1.
Characteristic | N=42 |
---|---|
Age in years, median (IQR) | 60 (56-71) |
Female | 28 (67%) |
Smoking status | |
Never | 3 (7%) |
Former | 36 (86%) |
Current | 3 (7%) |
ECOG Performance Status | |
0 | 4 (10%) |
1 | 38 (90%) |
# lines prior systemic therapy | |
0 | 15 (36%) |
1 | 14 (33%) |
2+ | 13 (31%) |
Prior local CNS therapy* | |
None | 21 (50%) |
Stereotactic radiosurgery | 16 (38%) |
Whole brain radiation therapy (WBRT) | 8 (19%) |
Craniotomy/resection | 4 (10%) |
Histology | |
Adenocarcinoma | 36 (86%) |
Squamous cell | 4 (10%) |
Poorly differentiated carcinoma | 2 (5%) |
Molecular alteration | |
KRAS | 14 (33%) |
EGFR | 6 (14%) |
ALK | 1 (2%) |
HER2 | 1 (2%) |
MET exon 14 | 1 (2%) |
Some patients received more than one treatment modality
IQR, interquartile range