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. Author manuscript; available in PMC: 2020 Jul 24.
Published in final edited form as: Med Lav. 2012 Jul-Aug;103(4):259–267.

Table 4 -.

Results of multiple regression models* on plasma concentrations (pg/g lipid) of polychlorinated-dibenzo-para-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), non-ortho-polychlorinated biphenyls (PCBs), and toxic equivalencies (TEQs) in the Seveso area, by residence zone, Dec 1992 - Mar 1994. Indicated are the relative changes (%) and their 95% confidence intervals (95% CIs)

Congener N Zone A Zone B Women Age (10 yrs) Former smokers Current smokers BMI (kg/m3)
% 95% CI % 95% CI % 95% CI % 95% CI % 95% CI % 95% CI % 95% CI
PCDDs
2,3,7,8-TCDD 110 1068 524, 2087 130 71, 210 113 52, 198 13 3, 24 11 −24, 63 6 −28, 58 46 −49, 316
1,2,3,7,8-PeCDD 108 −14 −43, 28 −8 −24, 11 24 0, 54 16 10, 23 −18 −36, 5 −5 −27, 3 −1 −3, 2
1,2,3,4,7,8-HxCDD 49 −26 −79, 159 −15 −39, 20 6 −28, 55 14 0, 30 11 −27, 70 23 −20, 89 −3 −8, 2
1,2,3,6,7,8-HxCDD **
1,2,3,7,8,9-HxCDD 109 −2 −39, 57 −1 −21, 23 16 −10, 50 8 0, 15 −32 −49, −9 −8 −32, 24 1 −2, 4
1,2,3,4,6,7,8-HpCDD 111 −10 −38, 33 −9 −24, 9 20 −2, 47 3 −3, 9 −28 −43, −9 −56 −65, −44 3 0, 5
OCDD 109 −9 −42, 42 −26 −40, −8 22 −4, 56 7 0, 15 −27 −45, −4 −41 −56, −22 0 −2, 3
PCDFs
2,3,7,8-TCDF 109 23 −13, 76 1 −15, 19 −7 −23, 13 −4 −9, 1 2 −18, 27 6 −15, 31 −2 −4, 1
1,2,3,7,8-PeCDF 115 8 −25, 55 5 −11, 25 −14 −29, 4 −4 −9, 1 −6 −25, 17 7 −13, 33 −1 −3, 2
2,3,4,7,8-PeCDF 111 −6 −28, 22 −8 −19, 4 12 −3, 29 16 12, 21 −10 −24, 5 −23 −34, −9 −1 −3, 0
1,2,3,4,7,8-HxCDF 109 −6 −31, 29 −5 −18, 10 14 −4, 35 13 8, 18 −12 −27, 7 −25 −38, −8 0 −2, 2
1,2,3,6,7,8-HxCDF 109 −2 −30, 37 −2 −16, 14 20 0, 43 11 6, 17 −5 −23, 16 −29 −42, −12 −1 −3, 1
1,2,3,7,8,9-HxCDF 116 26 −8, 73 4 −10, 21 −2 −17, 15 0 −5, 4 2 −16, 24 4 −14, 25 −2 −4, 0
2,3,4,6,7,8-HxCDF 110 35 −13, 110 10 −11, 36 19 −7, 51 1 −5, 8 −21 −40, 4 −25 −43, −2 0 −3, 2
1,2,3,4,6,7,8-HpCDF 109 −7 −38, 40 −8 −24, 12 −12 −29, 10 −4 −10, 1 5 −19, 35 −17 −36, 8 −1 −3, 2
1,2,3,4,7,8,9-HpCDF 117 35 0, 82 0 −12, 15 −4 −18, 12 −2 −6, 2 −3 −19, 16 9 −9, 29 −2 −4, 0
OCDF 108 −43 −72, 18 −4 −28, 29 −10 −36, 25 −12 −20, −4 9 −25, 61 −3 −34, 42 0 −4, 4
Non-ortho PCBs
33’44’-TCB (77) 109 63 −6, 183 −15 −30, 4 0 −20, 26 −5 −11, 1 5 −19, 38 7 −18, 39 −1 −4, 2
344’5-TCB (81) 111 25 −27, 115 −11 −30, 13 0 −24, 31 −7 −14, 0 −2 −28, 35 28 −6, 74 −2 −5, 1
33’44’5-PeCB (126) 109 10 −23, 58 4 −12, 23 18 −2, 43 17 11, 23 −20 −36, −1 −41 −53, −26 2 0, 4
33’44’55’-HxCB (169) 108 −11 −33, 19 −15 −25, −4 −15 −26, −1 21 16, 26 −12 −26, 3 −13 −26, 3 −4 −5, −2
TEQs
PCDDs 111 398 214, 687 54 24, 91 59 24, 103 12 5, 20 −1 −25, 31 −13 −35, 16 0 −3, 3
PCDDs/no 2378-TCDD 110 −7 −44, 52 −4 −24, 21 21 −7, 58 12 4, 20 −18 −39, 11 −37 −54, −14 −2 −5, 1
PCDFs 118 6 −46, 109 8 −20, 48 13 −20, 61 24 13, 37 2 −32, 53 −36 −57, −6 0 −5, 4
Non-ortho PCBs 118 66 −62, 622 30 −34, 154 22 −43, 163 41 14, 73 −11 −63, 115 −67 −86, −21 −1 −10, 8
Total 111 149 84, 237 20 4, 38 34 14, 58 14 9, 19 −7 −22, 12 −20 −34, −4 −1 −3, 1
Total/no 2378-TCDD 110 0 −25, 33 −4 −16, 10 17 0, 36 15 10, 20 −16 −29, 1 −31 −42, −17 −1 −3, 1

Abbreviations: BMI, body mass index; 95% CI, 95% confidence interval.

*

Dependent variables were loge-transformed. Relative change (%) was calculated with the formula: [exp(coefficient)−1]×100. Models contained the following covariates: zone of residence (reference: non-ABR); gender (reference: male); age (years/10); smoking (reference: never smokers); BMI (kg/m2). Each variable is adjusted for the others.

**

Undetectable in all plasma samples.