Table 2: Demographics and Allergic Clinical Characteristics.
n | Overall n=590 |
Pass n=545 |
Indeterminate n=15 |
Fail n=30 |
p | |
---|---|---|---|---|---|---|
Demographics | ||||||
Female, n (%) | 588 | 249 (42.3) | 231 (42.5) | 6 (40.0) | 12 (40.0) | 0.995 |
Age at challenge in years, mean (sd) | 590 | 10.2 (8.1) | 10.3 (8.0) | 10.9 (13.9) | 8.1 (6.4) | 0.317 |
Race, n (%) | 554 | 0.220 | ||||
White | 461 (83.2) | 428 (83.8) | 13 (86.7) | 20 (71.4) | ||
Asian | 57 (10.3) | 51 (10.0) | 0 (0.0) | 6 (21.4) | ||
Black or African American | 7 (1.3) | 7 (1.4) | 0 (0.0) | 0 (0.0) | ||
Other | 29 (5.2) | 25 (4.9) | 2 (13.3) | 2 (7.1) | ||
Hispanic/Latino, n (%) | 482 | 26 (5.8) | 24 (6) | 0 (0.0) | 2 (10.0) | 0.486 |
Allergic History | ||||||
Atopic Dermatitis, n (%) | 569 | 370 (65.0) | 340 (64.9) | 10 (66.7) | 20 (66.7) | 0.972 |
Seasonal allergies, n (%) | 570 | 348 (61.1) | 321 (61.0) | 8 (57.1) | 19 (63.3) | 0.925 |
Positive Birch Testing, n (%) | 259 | 194 (74.9) | 182 (75.8) | 5 (55.6) | 7 (70.0) | 0.362 |
Total IgE, mean (sd) | 451 | 633.2 (986.1) | 639.1 (1007.5) | 650.3 (824.7) | 521.5 (643.8) | 0.85 |
Almond History | ||||||
Almond-specific IgE, mean (sd) | 570 | 3.5 (9.4) | 3.1 (7.7) | 3.4 (5.6) | 11.2 (23.7) | <0.001 |
Ratio of Almond:Total IgE, mean (sd) | 441 | 0.01 (0.03) | 0.04 (0.12) | 0.01 (0.01) | 0.01 (0.02) | <0.001 |
Almond SPT in mm, mean (sd) | 570 | 4.0 (3.7) | 3.8 (3.6) | 3.6 (3.8) | 6.4 (5.6) | 0.001 |
History of Previous Almond Reaction, n (%) | 559 | 60 (10.7) | 51 (9.8) | 2 (14.3) | 7 (25.9) | 0.029 |
Other Allergic Sensitization | ||||||
Peanut IgE, mean (sd) | 503 | 27.9 (37.9) | 27.0 (37.3) | 14.9 (17.6) | 52.4 (49.2) | 0.003 |
Peanut SPT in mm, mean (sd) | 403 | 8.5 (6.8) | 8.4 (6.9) | 10.1 (5.0) | 10.2 (5.6) | 0.462 |
Peanut Allergy, n (%) | 197 | 69 (35.0) | 64 (35.6) | 1 (20.0) | 4 (33.3) | 0.766 |
Hazelnut IgE, mean (sd) | 522 | 14.9 (24.9) | 14.6 (24.8) | 12.4 (20.4) | 21.7 (30.4) | 0.369 |
Hazelnut SPT in mm, mean (sd) | 500 | 4.3 (4.8) | 4.3 (4.9) | 4.2 (4.6) | 3.9 (4.1) | 0.929 |
Pistachio IgE, mean (sd) | 525 | 10.9 (21.2) | 10.7 (20.9) | 7.1 (13.4) | 15.7 (28.9) | 0.420 |
Cashew IgE, mean (sd) | 531 | 9.2 (19.5) | 9.1 (19.2) | 8.8 (16.2) | 12.5 (24.8) | 0.677 |
Pecan IgE, mean (sd) | 532 | 5.3 (13.6) | 5.0 (12.9) | 10.8 (23.5) | 8.6 (19.5) | 0.131 |
Walnut IgE, mean (sd) | 541 | 10.8 (23.4) | 10.3 (22.1) | 16.9 (35.5) | 17.4 (36.1) | 0.203 |