Table 4.
Association between AD-related cognitive domains and actigraph sleep indices in the full cohort of non-demented individuals with DS (N=47)
| Adjusting for Mental Age | Adjusting for Mental Age and Chronological Age | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TST | WASO | SE | SFI | NOA | LOA | TST | WASO | SE | SFI | NOA | LOA | |||
| Working Memory | Free and Cued | Corr. | .088 | −.283 | .256 | −.123 | .094 | −.259 | .081 | −.265 | .225 | −.104 | .180 | −.132 |
| Sig. | .568 | .059 | .090 | .420 | .533 | .086 | .602 | .082 | .142 | .503 | .243 | .393 | ||
| Cued Recall Intrusions | Corr. | −.041 | .239 | −.208 | .121 | .049 | .291 | −.032 | .218 | −.174 | .102 | .127 | .175 | |
| Sig. | .789 | .114 | .171 | .428 | .747 | .052 | .838 | .155 | .258 | .510 | .410 | .257 | ||
| Rivermead | Corr. | −.072 | .073 | −.132 | .065 | .120 | .156 | −.075 | .083 | −.146 | .073 | .104 | −.132 | |
| Sig. | .639 | .634 | .386 | .670 | .434 | .305 | .628 | .593 | .344 | .640 | .502 | .393 | ||
| Digit Span Forward | Corr. | .111 | −.004 | .074 | −.087 | −.171 | −.066 | .110 | .001 | .069 | −.084 | −.185 | −.050 | |
| Sig. | .466 | .978 | .627 | .570 | .262 | .667 | .447 | .996 | .658 | .590 | .228 | .748 | ||
| Executive Functioning | Digit Span Backward | Corr. | −.060 | .048 | .086 | −.068 | .286 | −.154 | .056 | .063 | .069 | −.059 | .267 | −.108 |
| Sig. | .696 | .755 | .574 | .656 | .056 | .311 | .718 | .687 | .655 | .705 | .080 | .486 | ||
| Cat and Dog | Corr. | −.179 | .074 | −.153 | .110 | .009 | .358 | −.176 | .052 | −.128 | .096 | .058 | .299 | |
| Sig. | .239 | .631 | .315 | .472 | .953 | .016 | .253 | .736 | .409 | .536 | .710 | .049 | ||
| Motor Planning and Coordination | Purdue Pegboard | Corr. | .062 | −.179 | .198 | −.031 | .038 | −.302 | .055 | −.158 | .169 | −.011 | −.018 | −.215 |
| Sig. | .685 | .240 | .193 | .841 | .804 | .044 | .722 | .306 | .272 | .944 | .906 | .161 | ||
Note. TST = total sleep time; SE = sleep efficiency; WASO = wake after sleep onset; NOA = number of awakenings; SFI = sleep fragmentation index. Sig. = Significance (2-tailed); Corr. = Correlation. Bolded text, p <.05.