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. 2020 Jul 24;15(7):e0236378. doi: 10.1371/journal.pone.0236378

Table 1. Comparison of performances of deep learning and manual in internal and external test.

Internal test External test
Resnet50 Xception InceptionV3 Manual Resnet50 Xception InceptionV3 Manual
Sensitivity 0.90 0.85 0.93 0.62 0.86 0.86 0.90 0.62
specificity 0.90 0.97 0.95 0.97 1.0 0.90 0.90 0.95
PPV 0.90 0.97 0.95 0.96 1.0 0.90 0.90 0.93
NPV 0.90 0.87 0.93 0.72 0.87 0.86 0.90 0.70
F1-score 0.90 0.91 0.94 0.79 0.92 0.88 0.90 0.77
AUC 0.950 0.928 0.970 0.80 0.955 0.936 0.967 0.785
MCC 0.80 0.832 0.876 0.64 0.858 0.757 0.805 0.60

Abbreviations: PPV, positive predictive value; NPV, negative predictive value, AUC, area under the ROC curve, MCC, Matthews correlation coefficient.