Fig 3. Molecular interactions of 3CL pro hydrolase with co-crystallized inhibitors.

(a) 3D-Ligand interaction and (b) 3D molecular surface diagrams of co-crystallized peptide inhibitor in the binding site of 6LU7. (c) 3D-Ligand interaction and (d) 3D molecular surface diagrams of co-crystallized α-ketoamide inhibitor in the binding site of 6Y2F. The hydrogen bonds are represented as yellow dotted lines.