0 |
healed |
fibrocytes and collagen, multinucleated giant cells; capillaries; dense cellular connective tissue (dominant) |
1 |
midstage healing to healed |
capillaries; multinucleated giant cells; islands of loose matrix and dense collagen |
2 |
midstage healing |
macrophages (hemosiderin laden, cellular and substrate debris), fibroblasts, lymphocytes and admixture substrate (collagen and isolated fibrin fragments), multinucleated giant cells; admixture of neovascular buds and capillaries (dominant); loose cellular connective tissue |
3 |
early to midstage healing |
neovascular buds and capillaries; multinucleated giant cells; admixture of loose collagen (dominant) and fibrin |
4 |
early stage healing |
macrophages (erythrophagocytosis, cellular and substrate debris phagocytosis), fibroblasts, neutrophils, eosinophils, lymphocytes, multinucleated giant cells, plasma cells; neovascular buds; granulation tissue; admixture of fibrin and loose collagen |
5 |
residual blood to early stage healing |
neovascular buds; admixture of fibrin (dominant) and loose collagen |
6 |
residual blood |
cells and fibrin/protein; no vasculature; fibrin, no collagen |