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. Author manuscript; available in PMC: 2021 May 11.
Published in final edited form as: ACS Biomater Sci Eng. 2019 Sep 23;6(5):2588–2599. doi: 10.1021/acsbiomaterials.9b00895

Table 2.

Healing Score

0 healed fibrocytes and collagen, multinucleated giant cells; capillaries; dense cellular connective tissue (dominant)
1 midstage healing to healed capillaries; multinucleated giant cells; islands of loose matrix and dense collagen
2 midstage healing macrophages (hemosiderin laden, cellular and substrate debris), fibroblasts, lymphocytes and admixture substrate (collagen and isolated fibrin fragments), multinucleated giant cells; admixture of neovascular buds and capillaries (dominant); loose cellular connective tissue
3 early to midstage healing neovascular buds and capillaries; multinucleated giant cells; admixture of loose collagen (dominant) and fibrin
4 early stage healing macrophages (erythrophagocytosis, cellular and substrate debris phagocytosis), fibroblasts, neutrophils, eosinophils, lymphocytes, multinucleated giant cells, plasma cells; neovascular buds; granulation tissue; admixture of fibrin and loose collagen
5 residual blood to early stage healing neovascular buds; admixture of fibrin (dominant) and loose collagen
6 residual blood cells and fibrin/protein; no vasculature; fibrin, no collagen