Table 2.
Clinical characteristics of incident gastric cancers by first degree family history of gastric cancer (N=307)
| No family history (n=253) | Family history (n=54) | ||||
|---|---|---|---|---|---|
| N | % | N | % | p-valuea | |
| Age at diagnosis in years | |||||
| <60 | 5 | 2.0 | 2 | 3.7 | 0.29 |
| 60–69 | 84 | 33.2 | 17 | 31.5 | |
| 70–79 | 121 | 47.8 | 31 | 57.4 | |
| ≥80 | 43 | 17.0 | 4 | 7.4 | |
| Time to diagnosis in years | |||||
| < 5 | 71 | 28.1 | 18 | 33.3 | 0.22 |
| 5–10 | 62 | 24.5 | 10 | 18.5 | |
| 10–15 | 56 | 22.1 | 21 | 38.9 | |
| ≥15 | 64 | 25.3 | 5 | 9.3 | |
| Tumor grade | |||||
| Well differentiated | 8 | 11.4 | 3 | 15.0 | 0.90 |
| Moderately differentiated | 38 | 54.3 | 9 | 45.0 | |
| Poorly differentiated | 24 | 34.3 | 8 | 40.0 | |
| TNM stage at diagnosis | |||||
| 0–I | 28 | 31.8 | 5 | 20.8 | 0.33 |
| II | 8 | 9.1 | 3 | 12.5 | |
| III | 17 | 19.3 | 4 | 16.7 | |
| IV | 35 | 39.8 | 12 | 50.0 | |
P-values calculated by Mantel-Haenszel Chi-Square
Percentages for tumor grade and TNM stage at diagnosis do not include missing information