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. 2020 Jul 22;7(2):e001296. doi: 10.1136/openhrt-2020-001296

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Prehospital validation of the ESC 0/1-hour algorithm. The patients were assigned to rule-out, rule-in or the observation group according to the baseline hs-cTnT value or the 0–1 hour absolute change,²where high safety is demonstrated in the rule-out group. Summary of the calculations with corresponding 95 % CI are presented at the bottom. *, given a >3-hour symptom onset before the first hs-cTnT sample; †, rule-in and observation group combined; ǂ, rule-out and observation group combined. AMI, acute myocardial infarction; ESC, European Society of Cardiology; LR, likelihood ratio; hs-cTnT, high-sensitivity cardiac troponin T; NPV, negative predictive value; PPV, positive predictive value.