Table 2.

Difficulties associated with participant recruitment and their correction measures.

Study activity and associated difficulties or risks		Measures to correct or mitigate
Patient recruitment
	Low number of patients recruited or low involvement by health care professionals	Send weekly reminders
	Adult Mental Health Care Center professionals have little familiarity with the questionnaire	Attach the questionnaire in reminder emails for health care professionals
	Delay in the schedule due to slow recruitment	Expand to the maximum period of recruitment
Control participant recruitment
	Low access to paired patient controls	Create database of potential candidates who wanted to participate as controls
	Dependence on the pace of patient recruitment	Provide informative brochures