The role of aMCC in tenacious behaviors. Stronger functional connectivity between aMCC (labeled as ‘dACC’ by the authors) and supplementary motor is linked to lower levels of apathy (A) (Bonnelle et al., 2016); stronger functional connectivity between aMCC and ventral striatum is associated with grit (B) (Myers et al., 2016); spontaneous aMCC activity predicts grit (C)(Wang et al., 2017b); greater aMCC (labeled as ‘dACC’ by the authors) activity is associated with higher levels of persistence (D)(Kurniawan et al., 2010); aMCC signal is associated with willingness to exert more effort (E)(Bonnelle et al., 2016); aMCC activity increases during effort magnitude estimation (F)(Scholl et al., 2015); aMCC signal tracks the subjective value of effort exerted (G)(Chong et al., 2017); aMCC stimulation (yellow circle) increases the will to persevere (H)(Parvizi et al., 2013).