Table 1.

Characteristics of the included studies.

Study	Publication year	Study design	N	Gestational age, weeks	Umbilical cord blood pH value	Number of CP cases	Follow-up period
Carli et al. (32)	2004	Cohort study	43	≥37	pH < 7.00 or BD ≥ 12 mmol/L	13	12–36 months
Gluckman et al. (24)	2005	RCT	218	≥36	pH < 7.00 or BD > 16 mmol/L	52	18 months
Shankaran et al. (25)	2005	RCT	205	≥36	pH ≤ 7.00 or BD ≥ 16 mmol/L	34	18–22 months
Azzopardi et al. (26)	2009	RCT	323	≥36	pH < 7.00 or BD ≥ 16 mmol/L	81	18 months
Simbruner et al. (27)	2010	RCT	111	≥36	pH < 7.00 or BD > 16 mmol/L	14	18–21 months
Jacobs et al. (28)	2011	RCT	208	≥35	pH < 7.00 or BD ≥ 12 mmol/L	38	24 months
Perez et al. (33)	2013	Cohort study	68	≥36	pH < 7.1 and BD < −10 mmol/L	11	8.2–15.7 years
Filippi et al. (29)	2017	RCT	42	≥36	pH < 7.00 and/or BD > 16 mmol/L	13	18–24 months
Malla et al. (30)	2017	RCT	100	≥37	pH ≤ 7.00 and/or BD ≥ 16 mmol/L	29	19 months
Shankaran et al. (31)	2017	RCT	347	≥36	pH ≤ 7.00 or BD ≥ 16 mmol/L	47	18–22 months

BD, base deficit.