TABLE 1.

The overall conformation analysis of PPL in solvents.

Organic Solvent	Density (kg/m3)	Backbone RMSD (nm)	Pocket RMSD (nm)	Radius of gyration (nm)	Secondary structure relative content (%)			SASA (nm2)
					α -helix	β -sheet	loop	Hydrophobic	Hydrophilic	Total
Water	1,018.3	0.29	0.16	2.47	23.21	27.23	49.55	105.13	90.69	195.82
DMSO	1,083.9	0.21	0.16	2.51	24.55	27.23	48.21	112.72	89.25	201.98
PRG	9,58.2	0.34	0.29	2.45	16.52	22.32	61.16	120.47	63.1	183.57
EtOH	707.5	0.43	0.35	2.34	16.07	21.43	62.50	128.89	56	184.89