Table 3.
Fold changes in laminar gene expression of inflammation mediators after oligofructose administration.
| Inflammation mediator | Fold change | P value |
|---|---|---|
| Cytokine | ||
| IL-1β | 2.76 ↑ | 0.0022 |
| IL-6 | 2.63 ↑ | 0.0045 |
| IL-8 | 9.53 ↑ | 0.0007 |
| IL-10 | 0.61 | 0.0694 |
| TNF-α | 0.84 | 0.9879 |
| Chemokine | ||
| CXCL-1 | 5.04 ↑ | 0.0001 |
| CXCL-6 | 0.92 | 0.6314 |
| MCP-1 | 0.93 | 0.2987 |
| MCP-2 | 3.05 ↑ | 0.0004 |
| Adhesion molecule | ||
| ICAM-1 | 1.81 ↑ | 0.0478 |
| E-selectin | 2.90 ↑ | 0.0381 |
| Inflammatory molecule | ||
| COX-2 | 1.30 ↑ | 0.0259 |
| iNOS | 5.13 ↑ | 0.0225 |
| PAI-1 | 1.43 ↑ | 0.0480 |
Values displayed are mean fold change from control values.
NS, nonsignificant changed values; ↑, significant increased values.