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Cost estimates for different antibody manufacturing strategies, followed by either chromatographic or caprylic acid purification.
| CostAb | Downstream process | ||
| Chromatography | Caprylic acid | ||
| Fed-Batch | 62 USD/g | 46 USD/g | |
| Upstream process | Hybrid | 47 USD/g | 33 USD/g |
| Continuous perfusion | 89 USD/g | 42 USD/g | |
These estimates assume an annual production volume of 500 kg of antibodies.
