Table 1.

Serum lipid profile of db/db and db/+ mice after 15 weeks of G007-LK treatment.

	db/db		db/+
	Control n = 5 (4)	G007-LK n = 8 (6)	Control n = 9 (6)	G007-LK n = 9 (7)
TC (mmol/l)	2.68 ± 0.25###	1.95 ± 0.14**	1.74 ± 0.08	1.91 ± 0.10
LDL (mmol/l)	0.18 ± 0.04#	0.08 ± 0.01**	0.11 ± 0.01	0.10 ± 0.01
HDL (mmol/l)	0.92 ± 0.03##	0.71 ± 0.06*	0.62 ± 0.03	0.71 ± 0.04
TG (mmol/l)	1.78 ± 0.29###	1.66 ± 0.14	0.89 ± 0.09	0.76 ± 0.05
Glycerol (mmol/l)	0.31 ± 0.02###	0.26 ± 0.03	0.17 ± 0.01	0.18 ± 0.02
NEFA (mmol/l)	1.18 ± 0.19#	0.85 ± 0.12	0.58 ± 0.07	0.66 ± 0.09

Mean ± SEM, n numbers for measuring glycerol are indicated in parenthesis.

TC total cholesterol, LDL low-density lipoprotein cholesterol, HDL high-density lipoprotein cholesterol, TG triglycerides, NEFA nonesterified fatty acids.

*p < 0.05; **p < 0.01 vs. nontreated mice in each group, ^###p < 0.001; ^##p < 0.01; ^#p < 0.05 vs. db/+.