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. 2020 Jul 22;58:102909. doi: 10.1016/j.ebiom.2020.102909

Table 1.

Diagnostic classification according to the revised WHO case definitions.

Bacteriologically confirmed TB - Detection of AFB by microscopy of secretions or;- Identification of M. tuberculosis by culture or;- Identification of M. tuberculosis by Xpert.
Clinically diagnosed TB* - does not fulfil criteria for bacteriological confirmation but;
- Suggestive appearances on chest X-ray and;
- Favourable response to specific antituberculous therapy.
+/- Positive tuberculin skin test
+/-Suggestive histological appearances on biopsy material.

Clinically diagnosed TB cases had symptoms and signs suggestive of TB, did not fulfil the criteria for bacteriological confirmation of disease, had suggestive appearance on chest X-ray and failed to respond to empirical broad-spectrum antibiotics. Favourable response to antituberculous therapy was an integral part of the clinical TB diagnosis.