Table 3.
Methylation levels throughout the RFA treatment.
Mean methylation for genes: | Pre-RFA | post-RFA (1st follow-up) | Post-RFA (2nd follow-up) | P-value* |
---|---|---|---|---|
Biopsy site: | Barrett's | GEJ | GEJ | |
Methylation panel (%sum) | 67.3% (±59.2%) | 17.5% (±38.5%) | 2.28% (±8.51) | P<.001 |
ZNF345 | 26.9% (±33.7%) | 9.53% (±23.2%) | 0.917% (±3.55%) | P<.001 |
TFP12 | 19.8% (±24.2%) | 3.72% (±8.35%) | 0.869% (±4.74%) | P<.001 |
ZNF569 | 17.8% (±17.0%) | 4.64% (±10.4%) | 0.525% (±1.41%) | P<.001 |
- paired t-test with Bonferroni correction; GEJ, Gastroesophageal junction.