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. 2020 Jul 24;11(7):580. doi: 10.1038/s41419-020-02772-8

Table 1.

Summary of GSH associated miRNAs in cancer.

Name Associated cancer type Target Influence to GSH Model of evidence Reference
miR-27a Bladder cancer, colorectal cancer SLC7A11, ZBTB10 Up/Down Cell culture, animal models 42,43
miR-143 Colorectal cancer GPX Up Animal models 199
miR-17 Prostate cancer GPX2 Up Cell culture, animal models 56
miR-17-3p Prostate cancer GPX2 Up Cell culture, animal models 57
miR-196a Lung cancer GPX3 Up Cell culture, animal models 58
miR-921 Lung cancer GPX3 Up Cell culture 59
miR-124 Colorectal cancer GST Up Cell culture, animal models 48
Let-7a-5p Prostate cancer GST Up Cell culture, animal models 49
miR-92b-3p Prostate cancer GST Up Cell culture, animal models 49
miR-129-5P Colorectal cancer cells GST Up Cell culture 50
miR-144 Prostate cancer GST Up Cell culture, animal models 51
miR-153-1/2 Prostate cancer GST Up Cell culture, animal models 51
miR-302c-5p Colorectal cancer GST Up Cell culture 50
miR-3664-5p Colorectal cancer GST Up Cell culture 50
miR-3714 Colorectal cancer GST Up Cell culture 50
miR-513a-3p Colorectal cancer, lung cancer GST Up Cell culture 200
miR-590-3p/5p Prostate cancer GST Up Cell culture, animal models 51
miR-133a/b Bladder cancer, lung cancer, prostate cancer, colorectal cancer, ovarian cancer, head and neck squamous cell carcinoma GST Up Cell culture, animal models 52,53,201
miR-130b Ovarian cancer GST Up Cell culture 202
miR-186 Ovarian cancer GST Up Cell culture 203
miR-34b Prostate cancer MYC Up Cell culture 204
miR-K12-11 Kaposi’s sarcoma xCT Up Cell culture 205
miR-18a Hepatocellular carcinoma GCL Down Cell culture, animal models 37
miR-218 Bladder cancer GCL Down Cell culture 38
miR-21 Lung cancer GSH Down Cell culture 44
miR-24-2 Colorectal cancer GSH Down Clinical samples 45
miR-497 Cervical cancer GSH Down Cell culture 46
miR-503 Hepatocellular carcinoma GSH Down Cell culture 47
miR-152 Hepatocellular carcinoma GST Down Cell culture 39
miR-155 Lung cancer GST Down Cell culture 40
miR-326 Glioma PKM2 Down Cell culture 41
miR-125b Chronic lymphocytic leukemias GSH Unknown Cell culture 206