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. 2020 Jul 24;11(7):580. doi: 10.1038/s41419-020-02772-8

Table 5.

Summary of GSH, iron, NRF2, and ROS associated lncRNAs in cancer.

Control point Name Associated cancer type Target Influence to control point Model of evidence Reference
GSH Linc01419 Esophageal squamous cell carcinoma GST Up Clinical samples 144
Neat1 Hepatocellular carcinoma GST Up Cell culture 143
H19 Ovarian cancer GCLC, GCLM, GST Up/Down Cell culture, animal models 145
Xist Colorectal cancer GST Down Cell culture, animal models 48
Ror Breast cancer GST Down Cell culture, animal models 142
Iron Pvt1 Hepatocellular carcinoma miR-150/HIG2 Up Cell culture, animal models 146
H19 Myeloid leukemia miR-675 Inhibited by iron Cell culture 147
NRF2 Aatbc Bladder cancer NRF2 Down Cell culture, animal models 148
Kral Hepatocellular carcinoma KEAP1 Down Cell culture 91
Malat1 Multiple myeloma KEAP1 Down Cell culture, animal models 149
H19 Ovarian cancer NRF2 Down Cell culture, animal models 145
Scal1 Lung cancer Induced by NRF2 Cell culture 92
Loc344887 Gallbladder cancer Induced by NRF2 Cell culture 150
ROS Meg3 Lung cancer P53 Up Cell culture 154
Uca1 Bladder cancer miR-16 Down Cell culture 151
Gas5 Melanoma G6PD Down Cell culture 153
H19 Hepatocellular carcinoma MAPK/ERK signaling pathway Down Cell culture 152
Miat Neuroblastoma, glioblastoma MAPK7, FUT8, and MCL1 Unknown Cell culture 289295