Table 5.
Summary of GSH, iron, NRF2, and ROS associated lncRNAs in cancer.
Control point | Name | Associated cancer type | Target | Influence to control point | Model of evidence | Reference |
---|---|---|---|---|---|---|
GSH | Linc01419 | Esophageal squamous cell carcinoma | GST | Up | Clinical samples | 144 |
Neat1 | Hepatocellular carcinoma | GST | Up | Cell culture | 143 | |
H19 | Ovarian cancer | GCLC, GCLM, GST | Up/Down | Cell culture, animal models | 145 | |
Xist | Colorectal cancer | GST | Down | Cell culture, animal models | 48 | |
Ror | Breast cancer | GST | Down | Cell culture, animal models | 142 | |
Iron | Pvt1 | Hepatocellular carcinoma | miR-150/HIG2 | Up | Cell culture, animal models | 146 |
H19 | Myeloid leukemia | miR-675 | Inhibited by iron | Cell culture | 147 | |
NRF2 | Aatbc | Bladder cancer | NRF2 | Down | Cell culture, animal models | 148 |
Kral | Hepatocellular carcinoma | KEAP1 | Down | Cell culture | 91 | |
Malat1 | Multiple myeloma | KEAP1 | Down | Cell culture, animal models | 149 | |
H19 | Ovarian cancer | NRF2 | Down | Cell culture, animal models | 145 | |
Scal1 | Lung cancer | – | Induced by NRF2 | Cell culture | 92 | |
Loc344887 | Gallbladder cancer | – | Induced by NRF2 | Cell culture | 150 | |
ROS | Meg3 | Lung cancer | P53 | Up | Cell culture | 154 |
Uca1 | Bladder cancer | miR-16 | Down | Cell culture | 151 | |
Gas5 | Melanoma | G6PD | Down | Cell culture | 153 | |
H19 | Hepatocellular carcinoma | MAPK/ERK signaling pathway | Down | Cell culture | 152 | |
Miat | Neuroblastoma, glioblastoma | MAPK7, FUT8, and MCL1 | Unknown | Cell culture | 289–295 |