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. 2020 Jul 24;11(7):571. doi: 10.1038/s41419-020-02793-3

Fig. 6. Molecular mechanism of OSBPL3 in progression of CRC.

Fig. 6

Upregulation of OSBPL3 by HIF1A activates the RAS signaling pathway, and further promotes colorectal cancer progression by regulating the cell cycle and cytoskeleton.